Plasmid-mediated tetracycline resistance in Campylobacter jejuni: expression in Escherichia coli and identification of homology with streptococcal class M determinant.
نویسنده
چکیده
Plasmid pUA466, a 45-kilobase transmissible tetracycline resistance plasmid from Campylobacter jejuni was mapped with AvaI, AvaII, BclI, HincII, PstI, XhoI, and XbaI. The resistance determinant was cloned and expressed in Escherichia coli and was homologous with a class M determinant from Streptococcus spp.
منابع مشابه
Tetracycline resistance of Australian Campylobacter jejuni and Campylobacter coli isolates.
OBJECTIVES Tetracycline resistance in Campylobacter is encoded by the tet(O) gene and is usually associated with conjugative plasmids. Little was known about tetracycline resistance in Australian Campylobacter species, therefore we investigated this resistance in 41 Campylobacter jejuni and five Campylobacter coli strains from humans and healthy chickens. METHODS Tetracycline MICs were determ...
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عنوان ژورنال:
- Journal of bacteriology
دوره 165 3 شماره
صفحات -
تاریخ انتشار 1986